讲座编号:jz-yjsb-2016-y033
讲座问题:The studies of basket-shaped organic molecular vessels and their abilities of encapsulation
主 讲 人:颜志清 副教授 东伊利诺伊大学
讲座时间:2016年05月25日(周三)下昼14:00
讲座所在:阜成路西校区教一楼205室
加入工具:食物学院研究生
主理单位:食物学院
Dr. Zhiqing Yan is an Associate Professor of Chemistry at Eastern Illinois University. He received his B.S. degree from Fudan University, Shanghai China, and his Ph.D. degree from Miami University, Oxford OH, in the US. Prior to joining the faculty of EIU, Dr. Yan worked as post-doctor at the Ohio State University. His research is focused on the preparation of host molecules with a cavity, and then the study of their ability of encapsulating and releasing of smaller guests. His specific research interests include: organic synthesis, non-covalent interactions within the host-guest complex system, thermodynamics of the guest molecule traffic, and analytical techniques for studying host-guest interactions.
主讲内容:
Our dream of making molecules as powerful as enzymes to catalyze efficient chemical reactions remains to achieve. One of the approaches is to mimic the basket or pocket shape of enzymes to synthesize molecular hosts and then study their capability of encapsulating smaller guests. A number of hosts known as molecular vessels have been constructed, such as cavitands, carcerands, self-assembled capsules, and metal-assisted assemblies, to surround a guest molecule and their abilities of recognition have been studied. The studies involve a substantial amount of NMR techniques, including NMR titration, VT experiments of NMR, 2D-NMR such as NOESY, and DOSY. This presentation will introduce some specific examples in this field conducted in my research group at EIU.